Clinical research of oral compound polyethylene glycol electrolyte powder in different ways before colonoscopy
10.3760/cma.j.issn.1008-6706.2016.13.024
- VernacularTitle:不同方式口服聚乙二醇电解质散剂用于结肠镜检查前肠道准备的效果评价
- Author:
Xia CHEN
;
Chenmei XIA
;
Lingxiao JIN
;
Yufen ZHONG
;
Danhong HU
;
Xuying CHEN
;
Haiping XIE
- Publication Type:Journal Article
- Keywords:
Compound polyethylene glycol electrolyte;
Bowel preparation;
Colonscopy
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(13):2008-2011
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the different oral compound polyethylene glycol electrolyte powder on the effect of bowel preparation before colonoscopy.Methods A total of 602 inpatients or outpatients were selected from department of gastroenterology,and they were randomly divided into tranditional group(n =288)and improvement group(n =314).All patients took a dose of two box of compound polyethylene glycol electrolyte powder 4 hours before colonoscopy.Endoscopic doctor investigated the antibiotic tolerance,adverse reactions,heart rate,blood pressure,blood electrolytes and blood glucose during treatment in form of questionnaire with single blind Bosdon bowel preparation scale (BBPS)score.Results The BBPS scores of the tranditional group and improvement group were (7.03 ± 1.24)points,(7.82 ±1.12)points,the score of the improvement group was significantly higher than the traditional group(t =2.259,P <0.05).The taste scores were (1.89 ±0.07)points,(1.25 ±0.09)points (t =2.624,P <0.05),the fully taking rates were 90.28%,95.86%(χ2 =7.375,P <0.05 ),and the second taking rates were 88.54%,93.95%(χ2 =5.566,P <0.05).In contract,the score of adverse reactions of the improvement group was significantly lower than that of the traditional group [(2.58 ±0.07)points vs(2.22 ±0.09)points,t =2.068,P <0.05].There was no significant difference of colonoscopy time between the two groups[(10.78 ±4.34)min vs (9.89 ± 1.77)min,t =1.766,P >0.05 ],althought the improvement group was shorter than the tranditional group. Conclusion The modified way of oral compound polyethylene glycol electrolyte powder not only can improve the qulity of intestinal cleaning,but also acts as a more effective method in preparation of colonoscopy due to its high tolerance, good comfort,less pain and high acceptance of patients.Therefore,it is worthy of clinical promotion and application.