Changes of plasma mitochondrial coupling factor -6 and its significance in neonatal sepsis
- VernacularTitle:新生儿败血症血浆线粒体偶联因子-6浓度变化及临床意义
- Author:
Yu LIU
;
Xirong GAO
;
Shuangjie LI
- Publication Type:Journal Article
- Keywords:
Neonatal sepsis;
Mitochondrial coupling factor -6;
CRP
- From:
Journal of Chinese Physician
2016;(z1):30-32
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the variation of plasma mitochondrial coupling factor -6 and explore the significance in neonatal sepsis.Methods The study of 88 cases of pediatric inpatients in our hospital were divided into non-sepsis group (46 cases)and sepsis group (42 cases).CF-6 concentration in venous blood of all study subjects was determined by enzyme linked immunosorbent assay (ELISA).Re-sults The plasma CF-6 concentrations in peripheral venous blood of the patients with sepsis were signifi-cantly higher than those in non sepsis group(107.65 ±50.38)pg/ml vs (38.96 ±29.87)pg/ml,The con-centrations of CF-6 in the infected group were higher than those in the normal control group(P <0.05). Conclusions The concentration of mitochondrial coupling factor -6 in neonatal sepsis was significantly higher,and has a certain pathological and physiological significance in the pathogenesis of neonatal sepsis.
