The research of C1q/TNF-related proteins
- VernacularTitle:C1q 肿瘤坏死因子相关蛋白家族代谢功能的研究进展
- Author:
Hao JIA
;
Ting WU
;
Qin MA
;
Jianli ZHAO
- Publication Type:Journal Article
- Keywords:
CTRP family proteins;
Clycolipid metabolism;
Insulin resistance;
Lipid oxidation
- From:
Journal of Chinese Physician
2016;(z1):223-225
- CountryChina
- Language:Chinese
-
Abstract:
C1q /TNF-related proteins (CTRPs)belong to the same category of C1q /TNF-related protein family,mainly secreted by adipose tissue and widely expressed in human and rodent.Their function turned out to be metabolic modulation,cardiovascular system protection and suppression of inflammation.But for metabolic modulation,enhancing the synthesis of glycogen,promoting fatty acid uptake and oxidation,in-creasing insulin sensitivity is the major role of CTRPs playing in governing the metabolism.Each CTRP has its own unique tissue expression profile and nonredundant function in regulating sugar and /or fat metabo-lism.In this review we focus on the recent progress about the metabolic function of CTRPs.
