Efficacy and influence factors of 131 I in the treatment of differentiated thyroid carcinoma with lung metastasis
- VernacularTitle:131 I 治疗分化型甲状腺癌肺转移的疗效及影响因素
- Author:
Maimaiti ABUDUREHEMAN
;
Azhati JURETI
- Publication Type:Journal Article
- Keywords:
Differentiated thyroid carcinoma;
Metastasis;
Lung;
131 I
- From:
Journal of Chinese Physician
2016;(z1):42-45
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the differentiated thyroid carcinoma (DTC)pulmonary me-tastasis treated with radioactive iodine (131 I)the curative effect,analysis the relevant factors influencing the treatment effect.Methods Ninety -four patients with DTC pulmonary metastasis from thyroid cancer sur-gery after 131 I therapy,combined with the specific situation of the patients,the treatment of 131 for the first time for 3.7 ~7.4 GBq (mCi)100 ~200,using 1 oral medication on an empty stomach.after 6 months e-valuate the short-term curative effect.Analysis on age,gender,131 I treatment dose,for the first time before the first treatment serum thyroglobulin (Tg)levels and characteristics of pulmonary metastases to the effects of short-term curative effect of 131 I treatment.Results Ninety -four patients with DTC pulmonary metasta-sis for the first time after the end of 131 I treatment for 3 months short-term curative effect evaluation,a total of 30 cases cured (31%),29 cases improved (32%),35 cases (37%),effective rate was 63% (59 /94).During follow-up,94 patients with DTC lung turn 7 cases in new organs other than lung metastases,3 cases died.Female patients curative effect was better than that of men,for the first time before preoperative staging.treatment the curative effect of serum Tg level lower than level higher (P <0.05).Conclusions 131 I treatment of differentiated thyroid cancer metastasis has good curative effect,age,size of metastases, presence of other parts of the transfer,for the first time before 131 I treatment of Tg levels are the main factors influencing the effect of 131 I treatment,including age,metastases diameter less than 1 cm,no merger Other parts of the transfer for the first time,lower Tg level before 131 I therapy for patients with 131 I treatment effect is valuable.
