Hyperalgesia induced by Remifentanil
- VernacularTitle:瑞芬太尼引起的痛觉过敏
- Author:
Ying WANG
;
Gang LIU
- Publication Type:Journal Article
- Keywords:
Remifentanil;
Hyperalgesia;
Dexmedetomidine;
Review
- From:
Journal of Chinese Physician
2016;(z1):238-241
- CountryChina
- Language:Chinese
-
Abstract:
The use of opioids is proved to be associated with opioid-induced hyperalgesia(OIH), which is defined as an abnormal sense of pain characterized by a decrease in pain threshold and hypersensi-tivity to normal stimulus.There is an increasing number of studies based on the mechanisms,mainly about central glutaminergic system,spinal dynorphins and descending facilitation.The article summarized the mechanisms of OIH,suggested dose of remifentanil inducing OIH as well as major protective measures.
