Advances in brain network model of Parkinson's disease tremor mechanism
10.3760/cma.j.issn.1008-6315.2016.08.023
- VernacularTitle:帕金森病震颤机制脑部网络模型研究进展
- Author:
Yujie BIAN
;
Yuqi ZHOU
;
Yishuang CUI
;
Guolong ZHOU
;
Zifeng WEI
;
Yuxin ZHANG
;
Qian WANG
- Publication Type:Journal Article
- Keywords:
Parkinson’ s Disease;
Tremor;
Model
- From:
Clinical Medicine of China
2016;32(8):749-753
- CountryChina
- Language:Chinese
-
Abstract:
Objective Parkinson's disease( PD) is a common chronic neurodegenerative disease,with four major symptoms of resting tremor, muscle rigidity, slow motion and postural balance disorder?The pathogenesis of Parkinson's disease is still unknown?A large number of studies suggested that may be the result of the interaction of genetic factors,environmental factors,aging,immune factors,specifically involved in oxidative stress,mitochondrial damage,and other mechanisms?There were 50% patients characterized by tremors,tremor is the most difficult symptoms to treat of PD, but the mechanism is still under controversial, so it ’ s of great significance to understand the generation of PD tremor, which helps to promote the clinical treatment and diagnosis.
