Clinical effect of fuzhenghuayu capsule evaluated by liver instantaneous elastic imaging in treatment of early hepatocirrhosis
10.3760/cma.j.jssn.1673-4904.2016.06.017
- VernacularTitle:肝脏瞬时弹性成像技术评价扶正化瘀胶囊治疗早期肝硬化临床疗效的研究
- Author:
Danping HU
;
Yibing HU
;
Dong ZHANG
;
Xiaoting YE
;
Weiwei ZHANG
;
Rongquan FU
- Publication Type:Journal Article
- Keywords:
Liver cirrhosis;
Retrospective studies;
Fibroscan;
Fuzhenghuayu capsule
- From:
Chinese Journal of Postgraduates of Medicine
2016;39(6):537-539
- CountryChina
- Language:Chinese
-
Abstract:
Objective To estimate the clinical effect of fuzhenghuayu capsule in treatment of early hepatocirrhosis by liver instantaneous elastic imaging. Methods Eighty patients with early hepatocirrhosis were divided into experiment group and control group according to the treatment method with 40 cases each. All the patients in 2 groups were given the same antiviral treatment with entecavir dispersible tablets, and the patients in experiment group combined with fuzhenghuayu capsule. All treatment lasted for 6 months. The liver stiffness measurement (LSM) was measured before treatment and 1, 3 and 6 months after treatment by liver instantaneous elasticity imaging. The serum hyaluronic acid was measured, and the Child-Pugh score was evaluated at the same time. Results The LSM, hyaluronic acid and Child-Pugh scores 6 months after treatment in experiment group were significantly lower than those in control group:(19.3 ± 0.9) kPa vs. (29.6 ± 1.3) kPa, (215.6 ± 59.3)μg/L vs. (344.4 ± 39.6)μg/L and (2.1 ± 1.3) scores vs. (3.9 ± 0.9) scores, and there were statistical differences (P<0.05). No obvious adverse reactions related to the use of fuzhenghuayu capsule were found during the course of treatment. Conclusions Liver instantaneous elasticity imaging can be used to evaluate and monitor early hepatocirrhosis. Fuzhenghuayu capsule on patients with early hepatocirrhosis has a certain degree of curative effect.
