Pulmonary Hypertension Complicated by Pericardial Effusion on the Prognosis Among Maintenance Hemodialysis Patients
10.3969/j.issn.1006-5725.2016.10.011
- VernacularTitle:心包积液对合并肺高压的维持性血液透析患者预后的影响
- Author:
Zhilian LI
;
Xinling LIANG
;
Yuanhan CHEN
;
Ruizhao LI
;
Lixia XU
;
Wei DONG
;
Sijia LI
;
Zhonglin FENG
;
Wei SHI
- Publication Type:Journal Article
- Keywords:
Pulmonary hypertension;
Pericardial effusion;
Hemodialysis;
Mortality
- From:
The Journal of Practical Medicine
2016;32(10):1588-1591
- CountryChina
- Language:Chinese
-
Abstract:
Objective Pulmonary hypertension (PH) was an independent predictor of mortality and new onset cardiovascular events in maintenance hemodialysis (MHD) patients. Recent studies revealed PH complicated by pericardial effusion (PE) increased mortality in non-CKD (chronic kidney disease) population. No such evidence existed in MHD patients. Methods We enrolled 108 MHD patients with diagnosed PH by echocardiography (61 with PE) between 2009 and 2011. All patients had been followed-up for 2 years. The endpoints were all-cause mor-tality, cardiovascular (CV) mortality and new onset CV events. Results The mean age was (60.2 ± 14.1) years, 55.6% were males and SPAP was (53.0 ± 15.4) mmHg. 12.0% were severe PH and 1.9% were moderate-to-severe PE. The overall mortality, cardiovascular mortality and new on-set cardiovascular events in PE and non-PE group were 34.4% vs. 21.3%、 23.0% vs. 12.8% and 54.1% vs. 42.6%, respectively (P > 0.05). Kaplan-Meier curve showed there was no difference on all-cause mortality , CV mortality nor new-onset CV events between PE and non-PE group (Log Rank P > 0.05). Conclusions Compared with patients without PE, the presence of PE in patients with PH did not increase the mortality and worsen the cardiovascular outcome in MHD patients.
