Study on risk factors of recurrence in papillary thyroid microcarcinoma and papillary thyroid carcinomas with 1-2 cm diameter
10.3760/cma.j.issn.1000-6699.2016.05.008
- VernacularTitle:甲状腺乳头状微小癌和直径介于1~2 cm乳头状癌术后复发影响因素的比较
- Author:
Pingan SHI
;
Nan JING
;
Li ZANG
;
Weijun GU
;
Guoqing YANG
;
Xianling WANG
;
Qinghua GUO
;
Lijuan YANG
;
Zhaohui LYU
;
Jianming BA
;
Jingtao DOU
;
Yiming MU
- Publication Type:Journal Article
- Keywords:
Papillary thyroid carcinomas;
Recurrence
- From:
Chinese Journal of Endocrinology and Metabolism
2016;32(5):391-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore risk factors of recurrence in papillary thyroid microcarcinomas ( PTMC ) and papillary thyroid carcinomas with 1-2 cm diameter. Methods From January, 2008 to December, 2010 in PLA General Hospital, 323 eligible patients received first surgery and diagnosed pathologically with papillary thyroid cancer≤2 cm were analyzed retrospectively. According to rumor size, patients were divided into PTMC and PTC of 1-2 cm, which were investigated recurrence factors. Results Finally we indentified 320 PTC≤2 cm, including 218 (68.1%)PTMCand102(31.9%)PTCof1-2cmwithamedianfollow-uptimeof72.5(55-90)months.32cases (10%)of patients relapse, includig 22 cases(10%)in PTMC and 10 cases(9. 8%)in PTC of 1-2 cm. In the clinical characteristics analyses of PTC≤2 cm, the PTC of 1-2 cm was different from PTMC in age, lymph node metastasis and TNM stage. The univariate analysis showed that tumor location and lymph node metastasis influenced recurrence of PTMC and PTC of 1-2 cm,while tumor foci and extrathytoidal extension were risk factors of recurrence in PTMC but not in PTC of 1-2 cm. Lymph node metastasis was independent factor which influenced the recurrence of PTMC and PT C of 1-2 cm according to COX multivariate analysis. Conclusion Disease recurrence did not differ significantly between the PTMC and PTC of 1-2 cm and lymph node metastasis was an independent recurrence factor.
