Effect of alcoholism history on early post-operative cognitive function in elderly patients after general an-esthesia
- VernacularTitle:酗酒老年患者全麻术后早期认知功能的改变
- Author:
Yangyang ZHANG
;
Yingwei SUN
;
Shuhai HAN
- Publication Type:Journal Article
- Keywords:
Alcoholism;
Elderly;
General anesthesia;
Post-operative congnitive dysfunction
- From:
The Journal of Clinical Anesthesiology
2016;32(5):445-448
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of alcoholism history on the elderly patients’early cognitive function after lower abdominal or limbs surgery under general anesthesia through controlled clinical trials.Methods Sixty male patients aged 65-80 years of ASA grade Ⅰ or Ⅱ were selected un-dergoing lower abdominal or limbs surgery,30 cases with alcoholism history as alcohol group(group A),30 cases without alcoholism experience as control group (group C).All patients were anesthe-tized intravenously.The general data before and during operation,and the postoperative complications were recorded.The mini mental state examination(MMSE)was performed to assess the cognitive function 1d before and 1,7 d after surgery,then post-operative cognitive dysfunction(POCD)was compared between the two groups through analysis of the MMSE score.Results The MMSE score of 1,7 d after surgery in two groups was significantly lower than that of the preoperative(P < 0.05 ). Compared with the score 1 d after surgery,the score of 7 d post-operation was significantly higher in group A (P <0.05).The postoperative score in group A were significantly lower than that in group C 1,7 d after surgery (P <0.05).The incidence of POCD in group A were higher than that in group C 1,7 d after surgery (P <0.05 ).Conclusion Alcoholism history can increase the incidence of early cognitive dysfunction in elderly patients after general anesthesia.
