Changing resistance proifle ofProteus, Serratia, Citrobacter, Morganella andProvidencia isolates in hospitals across China：data from CHINET Antimicrobial Resistance Surveillance Program 2005-2014
- VernacularTitle:2005-2014年CHINET变形杆菌属、沙雷菌属、枸橼酸杆菌属、摩根菌属及普罗威登菌属细菌耐药性监测
- Author:
Jin LI
;
Zhidong HU
;
Fu WANG
;
Demei ZHU
;
Fupin HU
;
Ziyong SUN
;
Zhongju CHEN
;
Yi XIE
;
Mei KANG
;
Yingchun XU
;
Xiaojiang ZHANG
;
Zhaoxia ZHANG
;
Ping JI
;
Chuanqing WANG
;
Aimin WANG
;
Yuxing NI
;
Jingyong SUN
;
Yunsong YU
;
Jie LIN
;
Yunzhuo CHU
;
Sufei TIAN
;
Yuanhong XU
;
Jilu SHEN
;
Bin SHAN
;
Yan DU
;
Chao ZHUO
;
Danhong SU
;
Hong ZHANG
;
Jing KONG
;
Lianhua WEI
;
Ling WU
;
Yunjian HU
;
Xiaoman AI
;
Yanqiu HAN
;
Sufang GUO
;
Qing YANG
;
Bei JIA
;
Wenxing HUANG
- Publication Type:Journal Article
- Keywords: Proteus; Serratia; Citrobacter; Morganella; Providencia; bacterial resistance surveillance
- From: Chinese Journal of Infection and Chemotherapy 2016;16(3):284-293
- CountryChina
- Language:Chinese
- Abstract: Objective To understand the changing resistance proifle ofProteus,Serratia,Citrobacter,Morganella andProvidencia in hospitals across China according to the data from CHINET Antimicrobial Resistance Surveillance Program 2005-2014.Methods Antimicrobial susceptibility was tested by using Kirby-Bauer method or automatic minimum inhibitory concentration determination according to a uniifed protocol.Results A total of 21 663 clinical isolates were collected from January 2005 to December 2014. The proportion ofProteus andSerratia isolates increased with time from 1.41% in 2005 to 2.09% in 2014, and from 0.99% in 2005 to 1.28% in 2014 among all the isolates. No change was found for the proportion ofCitrobacter,Morganella, orProvidencia. Less than 10% of theProteus isolates were resistant to cefoperazone-sulbactam, piperacillin-tazobactam, ceftazidime, cefoxitin, amikacin and tigecycline. Less than 10% of theSerratia isolates were resistant to cefoperazone-sulbactam, piperacillin-tazobactam, amikacin and tigecycline. Less than 20% of theCitrobacter isolates were resistant to cefoperazone-sulbactam, piperacillin-tazobactam, cefepime, amikacin and tigecycline. Less than 10% of theMorganella isolates were resistant to cefoperazone-sulbactam, piperacillin-tazobactam, cefepime, amikacin and tigecycline. Less than 20% of theProvidencia isolates were resistant to cefoperazone-sulbactam, piperacillin-tazobactam, cefepime, cefoxitin and tigecycline.Conclusions The antibiotic resistance ofProteus,Serratia, Citrobacter,Morganella andProvidencia isolates in hospitals across China is growing during the period from 2005 to 2014. Strengthening infection control and rational antibiotic use are effective to slow the growth of drug resistance.