Investigation on inflammation reaction and vein thrombosis on rabbit ear vein with different drugs
- VernacularTitle:不同药物对兔耳缘静脉炎症及血栓形成的影响
- Author:
Qing DAI
;
Lunlan LI
;
Xuelan CHEN
- Publication Type:Journal Article
- Keywords:
inflammation;
venous thrombosis;
pharmaceutical preparation
- From:
Acta Universitatis Medicinalis Anhui
2016;51(6):910-912
- CountryChina
- Language:Chinese
-
Abstract:
To observe local inflammation reaction and vein thrombosis on rabbit ear vein with methotrexate , ceftri-axone sodium and normal saline .With the extension use of drugs , the numbers of inflammation reaction and throm-bosis in each group were increased , and antibiotic and chemotherapy drug group had a higher rate than the normal saline group .There was a statistically significant difference of the inflammation reaction between the three test groups on the 3rd and 7th day (P<0.05), and a statistically significant difference of thrombosis between the three test groups on the 7 th day ( P<0.05 ) .The physical-chemical properties of drugs and use of time were factors in-fluencing inflammation reaction and thrombosis .
