Transcranial magnetic stimulation promotes cognition among epileptics after traumatic brain injury
10.3760/cma.j.issn.0254-1424.2016.05.007
- VernacularTitle:不同频率低频重复经颅磁刺激对有癫痫发作史的颅脑损伤患者认知功能的影响
- Author:
Chenxia GUAN
;
Ganghua GUO
;
Zhe LI
- Publication Type:Journal Article
- Keywords:
Trauma;
Brain injury;
Transcranial magnetic stimulation;
Cognition;
Epilepsy
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2016;38(5):349-352
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of low-frequency, repetitive transcranial magnetic stimulation ( rTMS) at different frequencies on the cognitive function of traumatic brain injury patients with a history of epilepsy. Methods Sixty traumatic brain injury patients were randomly divided into a 0. 5 Hz group, a 1. 0 Hz group and a control group, each of 20. In addition to routine drug therapy and cognition training, the control group was given fake stimulation, the 0.5 Hz group was treated with 0.5 Hz rTMS, and the 1.0 Hz group was provided with 1.0 Hz rTMS for 4 weeks, eleven times per week. Before and after treatment, the cognitive function of all three groups was assessed using the Montreal cognitive assessment ( MOCA) , the Rivermead behavior memory test ( RBMT) and a symbol can-cellation test. The number of patients reporting headache or epilepsy during the treatment period was also counted. Results During the treatment, there was no headache case in any of the groups, and no significant difference was found in the occurrence of seizures. After the treatment, all of the measurements in all 3 groups had improved signifi-cantly. The average MOCA and RBMT scores in the 1.0 Hz group were all significantly better than those in the control group, but there was no significant difference between the 0.5 Hz group and the control group. The symbol cancella-tion test efficiency of the 1. 0 Hz group was not significantly better than that of the 0. 5 Hz and control groups. Conclusions Repeated 1.0 Hz transcranial magnetic stimulation can significantly improve cognition after traumatic brain injury among patients with a history of epilepsy without increasing the risk of seizures.
