The effects ofShenkang bolt on the IL-10 and IL-6 of the patients with continous ambulatory peritoneal dialysis
10.3760/cma.j.issn.1673-4246.2016.07.007
- VernacularTitle:肾康栓对持续性非卧床腹膜透析患者血清IL-10、IL-6因子的影响
- Author:
Siyi LI
;
Yong WU
- Publication Type:Journal Article
- Keywords:
End-stage renal disease;
Peritoneal dialysis,continuous ambulatory;
Shenkangbolt;
Immunomodulation
- From:
International Journal of Traditional Chinese Medicine
2016;38(7):599-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects ofShenkang bolt on the IL-10 and IL-6 of patients with continous ambulatory peritoneal dialysis (CAPD).MethodsA total of 60 patients with CAPD were divided into the control group (n=30) andShenkang bolt observation group (n=30). The control group was treated with convertional treatment of CAPD, low salt, low fat, low phosphorus and high quality diet. The observation group was treated withShenkang bolt based on control group treatment. The clinic effect was detected after treatment for 8 weeks. The serum creatinine was determinated by basic picric acid method, and blood urea nitrogen was determinated by urease test. The clinic and biochemical indicator of Scr, BUN, 24h urine volume, Kt/Vurea, RRF, and ultrafiltration volume were compared between the two groups. The IL-10 and IL-6 were detected by ELISA analysis.Results After treatment, IL-10 (19.56 ± 4.38μg/mlvs. 8.98 ± 2.05μg/ml,t=4.392,P<0.01) was significantly higher in observation group than that in control group, and IL-6 (21.82 ± 3.57μg/mlvs. 49.66 ± 5.26μg/ml,t=5.264,P<0.01) was significantly lower in observation group than that in control group. The RRF (7.86 ± 2.12vs. 5.31 ± 1.62;t=2.436, P=0.046) and ultrafiltration volume (421.37 ± 81.61 ml/dvs. 321.23 ± 71.94 ml/d;t=2.617, P=0.038) was significantly higher in observation group than those in control group. ConclusionShenkang bolt could help patients with CAPD balancethe immune, suppress inflammation and improve the RRF and ultrafiltration volume.
