Research progress of molecular genetics in T lymphoblastic leukemia/lymphoma
10.3760/cma.j.issn.1009-9921.2016.06.018
- VernacularTitle:T淋巴母细胞白血病／淋巴瘤分子遗传学研究进展
- Author:
Yanhua ZHANG
;
Jing LI
;
Yanfeng XI
- Publication Type:Journal Article
- Keywords:
T lymphoblastic leukemia/lymphoma;
Molecular genetics
- From:
Journal of Leukemia & Lymphoma
2016;25(6):381-384
- CountryChina
- Language:Chinese
-
Abstract:
T lymphoblastic leukemia/lymphoma (T-ALL/LBL) is a kind of lymphoblastic malignant tumors orientated in T-cell line with poor clinical effects. Its molecular genetics is mainly correlated with antigen receptor gene, abnormal chromosome, oncogene activation, tumor-suppressor gene inactivation and molecular pathways. This article will review the latest research progress of the molecular genetics in T-ALL/LBL to explore the index of prognosis and possible therapeutic targets.
