Restructuring morphogenesis protein-2 combined with nanocrystalline bone collagen bone material fusion between treating lumbar protrusion of the lumbar spine instability of clinical curative effect and safety evaluation
10.3760/cma.j.issn.1008-6315.2016.04.021
- VernacularTitle:重组人骨形态发生蛋白-2结合纳米晶胶原基骨材料治疗腰椎不稳症的临床效果及安全性评价
- Author:
Dezhi ZHU
- Publication Type:Journal Article
- Keywords:
Restructuring morphogenesis protein-2 bones;
M crystal collagen bone material;
Lumbar spinal instability syndrome;
Clinical curative effect;
Security
- From:
Clinical Medicine of China
2016;32(4):358-361
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore and analyze clinical efficacy and safety of restructuring morphogenesis protein-2 bones(rhBMP-2) combined with nanocrystalline collagen bone material(nHAC) fusion between treating lumbar protrusion of the lumbar spine instability.Methods Ninety cases of patients with lumbar instability syndrome who were treated in the People's Hospital of Heze from March 2013 to May 2013were selected and divided into restructure morphogenesis protein-2 combined with nanocrvstalline bone collagen bone material treatment group,purely in nanocrystalline collagen bone material treatment of the control group according to the random number table method,45 cases in each group.JOA evaluation results,intraoperative blood loss,postoperative infection,pulmonary complications within three months of the two groups were compared.Results The male proportion of experimental group and control group was 46.67％ and 48.89％respectively,the difference was significant(x2 =0.03,P =0.84).The excellent rate ofexperimental group and control group was respectively 93.33％,57.78％,the difference was significant (x2 =5.49,P ＜ 0.05).The incidence of deep vein thrombosis,infection rate,incidence of pulmonary complications of experimental group were 4.44％,8.88％,6.67％,of control group were 13.33％,24.44％,20.00％,the differences were significant (x2=5.12,3.78,3.56;P＜0.05).Conclusion Restructuring morphogenesis protein-2 bones combined with nanocrystalline collagen bone material treating lumbar fusion between the clinical curative effect of treating lumbar instability syndrome is better,with a lower incidence of complications,security is relatively high,compared to traditional surgery method has many advantages,can be used as a kind of ideal method used in the clinical work.
