Changes and significance of early lactate level and lactate clearance rate in patients with cardiac arrest syndrome
10.3760/cma.j.issn.1008-6706.2016.11.026
- VernacularTitle:心脏骤停综合征患者早期乳酸水平和乳酸清除率的变化及意义
- Author:
Li GONG
- Publication Type:Journal Article
- Keywords:
Cardiac arrest;
Cardiac arrest syndrome;
Lactic acid;
Lactate clearance
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(11):1703-1706
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the significance of early blood lactic acid and lactic acid clearance in patients with post-cardiac arrest syndrome(PCAS).Methods 87 cases were divided into the survival group(26 cases) and the death group(61 cases).The clinical data of two groups were analyzed statistically.Results The 6h blood lactate (8.46 ± 2.37) mmoL/L,6h blood lactate clearance rate (34.53 ± 14.75) ％,the residual alkali (-3.08 ± 3.68) mmol/L,6h SevO2 (68.35 ± 6.33) ％,APACHE Ⅲ score (19.64 ± 2.48) points in the survival group were significantly better than those of the death group [blood lactic acid value (12.32 ± 3.56) mmol/L,6h blood lactate clearance rate (27.71 ± 11.38) ％,the residual alkali (-5.61 ± 4.14) mmol/L,6h SevO2 (63.22 ± 5.94) ％,APACHE Ⅲ score (24.32 ± 5.33) points],with significant differences between two groups (t =5.99,2.36,2.73,3.66,5.62,all P ＜ 0.05).The 6h blood lactate clearance rate,6h SevO2 and APACHE Ⅲ score were independent risk factors for the prognosis of PCAS (OR =1.23,1.64,1.28,all P ＜ 0.05).Conclusion The early blood lactate clearance rate can be used as a sensitive indicator for evaluating the prognosis of PCAS.
