The clinical effect of the platelet rich plasma in treatment of chronic painless wound
10.3760/cma.j.issn.1008-6706.2016.11.009
- VernacularTitle:富血小板血浆治疗慢性难愈性伤口的临床研究
- Author:
Yongxi YANG
;
Jiaxiong FENG
;
Xiaotao HUANG
;
Yanran XU
;
Zeguang SUN
;
Chuzheng YAO
- Publication Type:Journal Article
- Keywords:
Platelet rich plasma (PRP);
Chronic difficult to heal the wound;
Wound
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(11):1637-1640
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe and analyze the clinical curative effect of the platelet rich plasma (PRP) in treatment of chronic difficult to heal the wound.Methods We selected 60 patients with chronic difficult healing wounds and they were divide into two groups at random,30 patients of A group,B group of 30 patients.All patients were given routine debridement,drainage and decompression treatment,B group was given autologous PRP wound injection and follow-up on the basis of conventional treatment.After injection of PRP,platelet count,platelet recovery and application of PRP granulation tissue growth and wound healing were observed.Results The wound healing effect at the 7th,14th,21 st day between the two groups,and compared with the 1 st day,the differences were statistically significant (A group:10.28％,22.16％,43.25％,65.78％;B group:18.75％,37.58％,61.84％,80.26％;X2:7.895,8.934,10.231,9.076,all P ＜ 0.05).Two groups of patients had obvious difference in healing time,in B group the average healing time was (12.6 ± 5.2) d,which in was (17.3 ± 7.4) d,the difference was statistically significant (t =1.932,P ＜ 0.05).Conclusion The PRP can effectively promote the wound repair of soft tissue,to promote healing of chronic difficult wound healing,the curative effect is distinct,it is worthy of clinical popularization and application.
