Updates on associating liver partition and portal vein ligation for staged hepatectomy
10.3760/cma.j.issn.1673-9752.2016.05.008
- VernacularTitle:联合肝脏分隔和门静脉结扎的二步肝切除术基础研究进展
- Author:
Lianxin LIU
- Publication Type:Journal Article
- Keywords:
Liver neoplasms;
Associating liver partition and portal vein ligation for staged hepatectomy;
Future liver remnant;
Liver regeneration;
Cytokines
- From:
Chinese Journal of Digestive Surgery
2016;15(5):441-443
- CountryChina
- Language:Chinese
-
Abstract:
The associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) procedure is a new surgical strategy.ALPPS is mainly used in the patients with insufficient future liver remnant (FLR) and advanced liver tumor.ALPPS provides fast and effective growth of FLR,so as to meet the normal liver function after surgery.The preliminary studies of liver regeneration of ALPPS rat model also have obtained certain achievements,a synergistic activation of the liver regeneration-associated signaling pathways,such as cytokines and transcription factors,contribute to the significant liver regeneration after ALPPS.In this paper,the advantages of ALPPS and preliminary research progress are summarized.
