Mechanism of anticarcinogenic function of ellagic acid in gastrointestinal cancers
10.3760/cma.j.issn.1673-422X.2016.06.020
- VernacularTitle:鞣花酸抗消化系统恶性肿瘤的作用机制
- Author:
Jinlu ZHAO
;
Guodong LI
;
Ming LIU
- Publication Type:Journal Article
- Keywords:
Ellagic acid;
Digestive system neoplasms;
Chemoprevention;
Molecular mechanisms of pharmacological action
- From:
Journal of International Oncology
2016;43(6):472-474
- CountryChina
- Language:Chinese
-
Abstract:
Recent in vitro and in vivo experiments have revealed that ellagic acid and its metabolites can inhibit the growth of digestive system malignant tumor cells by inhibiting tumor cell proliferation,inducing apoptosis,breaking DNA binding to carcinogens,blocking virus infection,disturbing inflammation,angiogenesis and drug-resistance processes required for tumor metastasis.Ellagic acid and its metabolites are potential chemoprevention and therapeutic drugs against human cancers.
