SOX7 and its expression and function in tumors
10.3760/cma.j.issn.1673-422X.2016.04.008
- VernacularTitle:SOX7及其在肿瘤中的表达和作用
- Author:
Huiping HE
;
Zumin XU
;
Chengnong GUAN
- Publication Type:Journal Article
- Keywords:
Transcription factors;
Genes,tumor suppressor;
SOX7
- From:
Journal of International Oncology
2016;43(4):271-273
- CountryChina
- Language:Chinese
-
Abstract:
SOX7 belongs to the SOX gene family.And it has been shown to regulate multiple biological processes.Studies have found that SOX7 gene is likely to be a tumor suppressor gene.In many tumors,SOX7 downregulation that inhibits proliferation,migration and invation of tumor via regulating the Wnt-β-catenin signaling pathway mediated the transcription process,which plays a significant role in tumorigenesis.
