Surface plasmon resonance sensing technology and its application in clinical diagnose
10.3760/cma.j.issn.1673-4181.2016.02.001
- VernacularTitle:表面等离子体共振传感技术及其在临床检验中的应用
- Author:
Juan ZHANG
;
Yuan PENG
;
Xiaoyi LYU
;
Zhixian GAO
- Publication Type:Journal Article
- Keywords:
Surface plasmon resonance sensor;
Biosensor;
Surface modification technique;
Clinical examination
- From:
International Journal of Biomedical Engineering
2016;39(2):65-73
- CountryChina
- Language:Chinese
-
Abstract:
Surface plasmon resonance (SPR) sensor technology,with its features of real-time,fast,no need for labeling,no background interference and non-destructive to samples,etc.,has been widely used in the field of biotechnology,medicine,environmental science and drug detection.This article gives an overview of the recent popular studies and their progress in SPR technology is reviewed,especially giving a detailed overview of the surface modification technique,related hyphenated techniques and application of SPR in clinical examination.Hyphenated techniques is discussed from three aspects of molecular imprinting technique,SPR based immunoassay and nucleic acids SPR biosensor as well.