Application of hematopoietic stem cell transplantation in the treatment of primary myelofibrosis
10.3760/cma.j.issn.1009-9921.2016.05.017
- VernacularTitle:造血干细胞移植在原发性骨髓纤维化治疗中的应用
- Author:
Zhiling YAN
- Publication Type:Journal Article
- Keywords:
Primary myelofibrosis;
Hematopoietic stem cell transplantation
- From:
Journal of Leukemia & Lymphoma
2016;25(5):314-317
- CountryChina
- Language:Chinese
-
Abstract:
Drugs and symptomatic and supportive treatment are still the main treatment in the primary myelofibrosis (PMF),but they can only improve symptoms without the natural course change of PMF.Hematopoietic stem cell transplantation (HSCT) is the only curable means to PMF,however,serious transplantrelated complications limit its extensive application in PMF patients.In this paper,donor selection process,pretreatment,successful transplantation factors and other factors on HSCT in PMF patients will be reviewed.