In Vitro Antibacterial Activity of Tanreqing Injection Combined with Cefuroxime Sodium Injection Against Staphylococcus Aureus
10.3870/j.issn.1004-0781.2016.07.011
- VernacularTitle:痰热清注射液联合头孢呋辛钠体外抗金黄色葡萄球菌作用
- Author:
Chunsheng YAN
;
Haiying XU
;
Qingge CHEN
;
Li WANG
;
Chaoyi LIU
- Publication Type:Journal Article
- Keywords:
Tanreqing injection;
Cefuroxime sodium injection;
Antibacterial effect;
Inhibitory concentration index,fractional;
Staphylococcus aureus
- From:
Herald of Medicine
2016;35(7):728-731
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the in vitro antibacterial effect of tanreqing injection combined with cefuroxime sodium injection against staphylococcus aureus. Methods The MIC of tanreqing injection or cefuroxime sodium injection against staphylococcus aureus was detected by microamount dilution method.The antibacterial activity of tanreqing injection combined with cefuroxime sodium injection was determined by a chess board dilution method and assessed according to FIC index. Results The MIC of tanreqing injection and cefuroxime sodium injection against staphylococcus aureus was 1∶256 and 2 μg . mL-1 , respectively. While combined with each other, the MIC of tanreqing injection and cefuroxime sodium injection against staphylococcus aureus was 1∶4 096 and 0. 125 μg . mL-1 , respectively. The FIC index of tanreqing injection combined with cefuroxime sodium injection against staphylococcus aureus was 0. 125. Conclusion Tanreqing injection has a synergistic antibacterial effect against staphylococcus aureus when it was combined with cefuroxime sodium injection.
