Optimization of Extraction for Flavonoids from Coreopsis Tinctoria Nutt.by Response Surface Methodology
10.3870/j.issn.1004-0781.2016.07.022
- VernacularTitle:响应面分析法优化新疆两色金鸡菊中总黄酮提取条件?
- Author:
Xincheng YAO
;
Heng WANG
;
Ruikun SHI
;
Beibei WANG
;
Hui TANG
- Publication Type:Journal Article
- Keywords:
Coreopsis tinctoria Nutt.;
Flavonoids;
Response surface method
- From:
Herald of Medicine
2016;35(7):765-768
- CountryChina
- Language:Chinese
-
Abstract:
Objective Response surface methodology ( RSM ) was applied to optimize the ultrasonic extraction conditions for flavonoids from Coreopsis tinctoria Nutt. Methods The influence factors of ultrasonic extraction were evaluated using the Box-Behnken central component experiments and analyzed by RSM. Results The optimum extraction conditions were confirmed as follows:extraction time 30. 0 min, ratio of liquid to solid 21∶1, concentration of ethanol 60%. The yield of flavonoids under this condition was (4.65±0.036)% (n=3). Conclusion The flavonoids could be extracted with stability and higher yield from Coreopsis tinctoria Nutt under optimized conditions.
