A Case of Lissencephaly Dignosed by Magnetic Resonance Imaging.
- Author:
In Yang PARK
1
;
Hyun Jeong KIM
;
Jeong KIM
;
Hyun Young AHN
;
Jong Chul SHIN
;
Soo Pyung KIM
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine Catholic University of Korea, Korea. jcshin@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Lissencephaly;
Ventricular Dilation;
Antenatal Diagnosis
- MeSH:
Cerebral Cortex;
Chromosome Aberrations;
Classical Lissencephalies and Subcortical Band Heterotopias;
Dandy-Walker Syndrome;
Female;
Humans;
Infant;
Karyotype;
Lissencephaly*;
Magnetic Resonance Imaging*;
Prenatal Diagnosis;
Ultrasonography
- From:Korean Journal of Perinatology
2003;14(4):433-437
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lissencephaly is a rare disorder that is characterized by the disorganized and unlayered cortex. The cause of this disorder is related to chromosomal abnormalities or infection. The pathogenesis of lissencephaly is faulty migration of neuroblast. Lissencephaly is associated with Dandy-Walker syndrome and Miller-Dieker syndrome. A woman at 35 weeks of gestaion was transferred to our hospital due to abnormal antenatal sonographic findings (ventricular dilation and decreased sulci in cerebral cortex after 31 weeks of gestation). The antenatal studies showed none-specific findings. The infant was diagnosed lissencephaly by postnatal MRI evaluation and showed normal karyotype. We report the prenatal diagnosis of lissencephaly case with a literature.
