The expression of the tryptase in the plasma of the brain traumatic patients

VernacularTitle:颅脑创伤患者血浆中类胰蛋白酶含量测定的临床意义
Author: Jianzhong GUO ; Yao WEI ; Rulei GU ; Dongliang GUO ; Hongming JI
Publication Type:Journal Article
Keywords: brain trauma; tryptase; FEIA
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(15):2275-2277
CountryChina
Language:Chinese
Abstract: Objective To detect the expression of the tryptase in the plasma,and study the meaning in brain traumatic patients.Methods There were two groups:the brain traumatic group(40 patients)and the control group (20 health people).The content of plasma tryptase was determined by fluorescence enzyme immunoassay..Results The level of plasma tryptase had no statistical significance in control group(2.97 ±1.05)μg/L compared with the brain traumatic group(3.03 ±1.39)μg/L,however there had statistical significance comparing with sever brain traumatic patients(3.84 ±0.52μg/L)(t =3.32,P <0.05).4 cases of death in patients with severe head injury group content of tryptase (5.85 ±1.05)μg/L,which was significantly higher than the group of 16 cases of injury in severe head injury after 2 months still alive with the content of serum tryptase (2.49 ±0.52)μg/L,the difference was statistically significant (t =8.13,P <0.01).Conclusion The plasma tryptase level in sever brain traumatic patients increased significantly,and might be of importance for treatment strategies and prognosis.