Research on platelet-derived growth factor and diabetic foot
10.3760/cma.j.issn.1008-6706.2016.15.042
- VernacularTitle:血小板衍生生长因子与糖尿病足的研究进展
- Author:
Rendong ZHENG
;
Chao LIU
- Publication Type:Journal Article
- Keywords:
Platelet -derived growth factor;
Vessel;
Nerve;
Ulcer;
Diabetic foot
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(15):2391-2393
- CountryChina
- Language:Chinese
-
Abstract:
Platelet -derived growth factor (PDGF)is an important factor of promoting cell growth which has a physiological role ranging from DNA synthesis,cell mitosis inducement,promotion on a variety of extracellular matrix accumulation as well as impact on the cell phenotype and growth.Studies showed that PDGF played an important role in growth and proliferation of vascular and nerve.It has a significant effect on accelerating tissue repair and promoting healing of chronic diabetic foot ulcers.