The effect of long term home non-invasive positive pressure ventilation in patients with stable severe chronic obstructive pulmonary disease
10.3969/j.issn.1671-8348.2016.17.025
- VernacularTitle:家庭无创机械通气对稳定期重度慢性阻塞性肺疾病患者的疗效观察
- Author:
Jie YANG
;
Yuanping CAI
;
Jianwu HU
;
Qiaofa LU
- Publication Type:Journal Article
- Keywords:
pulmonary disease,chronic obstructive;
home non-invasive positive pressure ventilation;
blood gas index
- From:
Chongqing Medicine
2016;45(17):2377-2379
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of long term home non-invasive positive pressure ventilation (HNIPPV ) in stable severe chronic obstructive pulmonary disease (COPD) .Methods Forty-two patients with stable severe COPD after hospital dis-charge were divided into 2 groups :The observation group (conventional treatment + HNIPPV ,22 patients) and control group (con-ventional treatment ,20 patients) .Parameters before and after one year follow-up observation were compared ,which includes arterial bloods gases ,lung function test ,6-min walking distance(6MWD) ,dyspnea grade ,scoring for emotional disorders ,the hospitalization rates .Results PaCO2 ,PaO2 ,6MWD ,dyspnea grade ,scoring for emotional disorders ,the hospitalization rates improved after one year in the observation group (P < 0 .05) .There were no significance of FVC and FEV1 between the two groups after one year . There were no patients who were dead or exited with other reason after one year in the two groups .Conclusion Long term HNIP-PV could decrease exacerbations ,respiratory failure and increase life quality ,this therapy is effective and safe for patients with sta-ble severe COPD .
