Clinical characteristics of pleural effusion in children withMycoplasma pneumoniae
10.3969/j.issn.1000-3606.2016.06.008
- VernacularTitle:儿童肺炎支原体性胸腔积液特点分析
- Author:
Xiaojing HAO
;
Quanheng LI
;
Wenjie GAO
;
Jinying LI
;
Weiran DONG
;
Yanyan WANG
;
Shuhua AN
- Publication Type:Journal Article
- Keywords:
pleural effusion;
lactic acid;
Mycoplasma pneumoniae;
child
- From:
Journal of Clinical Pediatrics
2016;34(6):430-433
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical characteristics of pleural effusion caused byMycoplasma pneumoniae in children.MethodsThe clinical data from children with pleural effusion caused byMycoplasma pneumoniae were retrospectively analyzed. Differences of clinical characteristics in children with pleural effusion caused byMycoplasma pneumoniae infection and non-Mycoplasma pneumoniae infection were compared. Moreover, multiple logistic regression analysis was performed on the factors that were identified to have statistical differences in single factor analysis. Receiver operating characteristic (ROC) curve was performed and the diagnostic boundary value of each factor and the diagnostic accuracy of the regression model were calculated.ResultsThere were statistical differences between children with pleural effusion caused byMycoplasma pneumoniae infection and by non-Mycoplasma pneumoniae infection in age, white blood cell count, lactic dehydrogenase (LDH), levels of IgA and IgM, and the proportion of multiple nuclei, glucose and lactic acid (LAC) in pleural effusion, pleural thickening, and formation of ifbrous separation (allP?0.05). Multifactor logistic regression found the differences of age, levels of IgM and LDH, level of LAC are statistically different between the two groups (allP0.05), with their diagnostic boundary value of 3.92 years old, 1.29 g/L, 367 U/L and 4.02 mmol/L, respectively.ROC under the curve (AUC) was 0.887 (95%CI: 0.830-0.944,P0.001).ConclusionIn children having pleural effusion caused by pneumonia of unknown pathogen, if their age is?>?3.92 years, serum IgM?>?1.29 g/L, LDH?>?367 U/L and pleural effusion LAC?4.02 mmol/L, Mycoplasma pneumoniae infection should be highly suspected.