A study of the relationship between iodine intake levels and hypothyroidism of pregnant women in Qingdao
10.3760/cma.j.issn.1008-6706.2016.15.003
- VernacularTitle:山东省青岛地区妊娠早期妇女碘营养状况与甲状腺功能减退症的相关性分析
- Author:
Liyan ZHANG
;
Xiufen ZHAO
;
Xiao ZHOU
- Publication Type:Journal Article
- Keywords:
iodine;
pregnancy;
hypothyroidism;
thyroid peroxidase Antibody
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(15):2248-2251
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the urinary iodine level and the thyroid function of early pregnant women in Qingdao,to explore the relationship between the iodine nutritional status and hypothyroidism.Methods 326 early pregnant women (<12 gestational weeks)were collected.The urinary iodine concentration and serum thyroid stimulating hormone (TSH),free thyroxine (FT4 ),thyroid peroxidase antibody (TPOAb)were detected. Results The median of urine iodine of pregnant women was 176.57μg/L,and the ratios of iodine deficient,iodine adequate,iodine more than adequate and iodine excessive groups were 3 8.65%,41.10%,15.95% and 4.30%.The total ratio of innormal urine iodine was 58.9%(192 /326).The differences between the ratios of the iodine deficient group,iodine excessive group and iodine adequate group both had statistically significant(χ2 =4.308,P <0.05;χ2 =4.826,P <0.05 ).There was no effect of iodine intake levels on serum thyroid peroxidase antibody.Conclusion There is no iodine deficiency among early pregnant women in Qingdao,but still individuals expose iodine deficiency.Iodine deficiency and iodine excessive are the risk factors of hypothyroidism during early pregnancy women,so we commend to detect the urinary iodine level.
