Clinical features of congenital hepatic ifbrosis in children

VernacularTitle:儿童先天性肝纤维化的临床特点
Author: Xin WU ; Xiaorang DU ; Jinfang DING ; Mengjin WU ; Shengqiang LUO ; Xingzhong FENG
Publication Type:Journal Article
Keywords: congenital hepatic ifbrosis; Caroli disease; ductal plate malformation
From: Journal of Clinical Pediatrics 2016;34(6):444-448
CountryChina
Language:Chinese
Abstract: Objective To explore the clinical features of congenital hepatic fibrosis (CHF) in children.MethodsA total of 111 patients diagnosed with CHF during January 2002 to June 2015 were included and divided into children group and adult group according to the age at diagnosis. The clinical data including gender, age, clinical symptoms, signs, laboratory examinations, and imaging characteristics were retrospectively analyzed and compared between two groups.ResultsThere were high incidences of splenomegaly and liver cirrhosis in both children and adult groups, and no difference was found between two groups (P>?0.05). The fatigue, jaundice, and hepatosplenomegaly were more common in children group while the renal cyst and liver cyst were more common in adult group, and the differences were statistically signiifcant (P all?