The curative effect of albendazole combined with cimetidine in the treatment of hepatic echinococcosis

VernacularTitle:阿苯达唑联合西咪替丁治疗肝包虫病的疗效观察
Author: Yao SHENG ; Zhiping TANG ; Fang ZHOU ; Tongsheng YANG
Publication Type:Journal Article
Keywords: Albendazole; Cimetidine; Liver echinococcosis
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(14):2126-2129
CountryChina
Language:Chinese
Abstract: Objective To observe the clinical effect of albendazole combined with cimetidine in the treatment of hepatic hydatid disease.Methods 60 cases with liver hydatid disease from 2010 to 2014 wrer selected,and they were randomly divided into two groups,30 cases in each group.The control group was treated with albendazole tablets,2 times daily,2 capsules/time.The treatment group was intravenously injected cimetidine based on the treatment of the control group.Before and after treatment,the ultrasound imaging changes and clinical effect were observed.Results In the control group,the total effective rate was 83.33%(25 /30).In the treatment group, the total effective rate was 96.67%(29 /30).The total effective rate between the two groups had statistically signifi-cant difference(χ2 =9.842,P <0.01).Conclusion Albendazole combined with cimetidine in treatment of hepatic hydatid disease has good curative effect,which can be viewed as first choice in the treatment of hydatid disease.