Efficacy and safety analysis of safflower yellow injection in the treatment of stable angina pectoris
10.3760/cma.j.issn.1008-6706.2016.14.033
- VernacularTitle:注射用红花黄色素治疗稳定型心绞痛疗效和安全性分析
- Author:
Shuqin WANG
;
Jingsheng NIU
- Publication Type:Journal Article
- Keywords:
Angina pectoris;
Safflower yellow pigment;
Treatment outcome
- From:
Chinese Journal of Primary Medicine and Pharmacy
2016;23(14):2205-2208
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the efficacy and safety of safflower yellow injection in the treatment of sta-ble angina pectoris.Methods 70 patients with stable angina pectoris were selected and divided into observation group and control group by random number table method,35 cases in each group.The observation group used injection of safflower,and the control group used Xuesaitong.The effect was compared between the two groups.Results The total effective rate of the observation group was 94.3%,which was higher than 74.3% of the control group,the differ-ence was statistically significant(χ2 =5.285,P <0.01).The clinical indexes of the two groups after treatment were significantly improved than before treatment,the differences were statistically significant (t =13.021,25.407,3.376, 3.930,7.119,10.163,18.044,3.765,3.124,6.096,all P <0.05).The angina attack times of the observation group was less than that of the control group ,the dosage of nitroglycerin was lower than that of the control group ,the differences were statistically significant(t =4.686,6.568,all P <0.05).The incidence rate of adverse reaction was 5.7% in the observation group,compared with the control group of 8.6%,the difference was not statistically signifi-cant(χ2 =0.729,P >0.05).Conclusion The injection of safflower yellow pigment in the treatment of stable angina pectoris has high safety.
