The effect of compound sophora injection in the treatment of advanced gastric cancer patients with peritoneal effusion

VernacularTitle:复方苦参注射液腹腔灌注治疗胃癌晚期腹腔积液疗效观察
Author: Xiaomei LI ; Yan GU
Publication Type:Journal Article
Keywords: Stomach neoplasms; Ascites; Injections,intraperitoneal; Compound sophora injection
From: Chinese Journal of Primary Medicine and Pharmacy 2016;23(14):2213-2215
CountryChina
Language:Chinese
Abstract: Objective To investigate the effect of intraperitoneal injection of compound sophora injection in the treatment of advanced gastric cancer patients with malignant peritoneal effusion.Methods 60 advanced gastric cancer patients with peritoneal fluid were randomly divided into two groups according to the different treatment meth-ods.A group of compound sophora injection with intraperitoneal therapy(group A),treatment 2 times per week for four weeks,Another group of compound sophora injection with vein therapy (group B),for 4 consecutive weeks.The efficacy of the two groups was compared.Results The effective rate of group A was 58.1%,which was higher than 27.6% of group B,the difference was statistically significant(χ2 =5.69,P <0.05).Conclusion Intraperitoneal perfusion with compound sophora injection can improve the effect in the treatment of peritoneal effusion in patients with advanced gastric cancer,and the adverse reaction is mild,it is worthy of clinical application.