Effects of acupuncture and rehabilitation therapy on the expression of growth associatedprotein-43 and synaptophysin at the injury site of cerebral palsy rats
10.3969/j.issn.2095-4344.2016.27.007
- VernacularTitle:针刺康复疗法影响脑性瘫痪模型大鼠大脑病变组织生长相关蛋白43和突触小泡蛋白的表达
- Author:
Yujin HOU
;
Haopeng KANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2016;20(27):3999-4005
- CountryChina
- Language:Chinese
-
Abstract:
RESULTS AND CONCLUSION:(1) Motor function: The motor function scores were better in the acupuncture + rehabilitation group than in the model, acupuncture, and rehabilitation groups (P< 0.05). (2) Growth associated protein-43 and synaptophysin expression: immunohistochemical staining revealed that compared with the model group, growth associated protein-43 expression at 2-4 weeks and synaptophysin expression at 4 and 5 weeks were higher in the acupuncture and acupuncture + rehabilitation groups(P<0.05); the increase in above expression was most significant in the acupuncture + rehabilitation group (P<0.05). (3) Results confirmed that acupuncture combined with rehabilitation promoted growth associated protein-43 and synaptophysin expression in rats with cerebral palsy and exerted neuroprotective effect.