Diagnosis of Churg-Strauss Syndrome Presented With Neuroendocrine Carcinoma: A Case Report.
10.5535/arm.2017.41.3.493
- Author:
Dayun PARK
1
;
Ho Jun LEE
;
Kwang Hoon LEE
;
Bum Sun KWON
;
Jin Woo PARK
;
Ki Yeun NAM
;
Kyoung Hwan LEE
Author Information
1. Department of Physical Medicine and Rehabilitation, Dongguk University College of Medicine, Seoul, Korea. hjrhee1@gmail.com
- Publication Type:Case Report
- Keywords:
Churg-Strauss syndrome;
Thymic neuroendocrine carcinoma;
Polyneuropathy
- MeSH:
Asthma;
Biopsy;
Blood Vessels;
Carcinoma, Neuroendocrine*;
Churg-Strauss Syndrome*;
Diagnosis*;
Dyspnea;
Eosinophilia;
Eosinophils;
Hematologic Tests;
Humans;
Lower Extremity;
Middle Aged;
Paresthesia;
Peripheral Nervous System Diseases;
Polyneuropathies;
Pyoderma;
Sinusitis;
Skin;
Systemic Vasculitis;
Thorax;
Thymectomy;
Thymus Neoplasms
- From:Annals of Rehabilitation Medicine
2017;41(3):493-497
- CountryRepublic of Korea
- Language:English
-
Abstract:
Churg-Strauss syndrome (CSS) is a rare systemic vasculitis that affect small and medium-sized blood vessels and is accompanied by asthma, eosinophilia, and peripheral neuropathy. This report describes a case of a 52-year-old man who had a history of sinusitis, asthma, and thymus cancer and who had complained of bilateral lower extremity paresthesia and weakness for a month. Peripheral neuropathy was detected by electrodiagnostic studies. Resection of a mediastinal mass, which was diagnosed as thymic neuroendocrine carcinoma, was performed five months before his visit. After thymectomy, peripheral blood tests revealed a gradual increase in eosinophils. Two months after surgery, he was admitted to the hospital for dyspnea, and nodules of focal consolidation were found in his chest X-ray. One month later, pyoderma occurred in the right shin, and the skin biopsy showed extravascular eosinophilic infiltration. He was diagnosed with CSS after thymectomy, and we report a very rare case of CSS presented with thymic neuroendocrine carcinoma.
