CT-guided percutaneous needle lung biopsy versus surgical specimens in the diagnosis of different patholog-ical types of lung cancer
10.16571/j.cnki.1008-8199.2016.05.011
- VernacularTitle:不同途径获取肺癌组织对病理类型诊断的差异性分析
- Author:
Yafang LIU
;
Ze XING
;
Yong SONG
- Publication Type:Journal Article
- Keywords:
Percutaneous needle lung biopsy;
Lung cancer;
Surgery;
Pathological type
- From:
Journal of Medical Postgraduates
2016;29(5):500-503
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study was to investigate the diagnostic value of CT-guided percutaneous needle lung biopsy ( PN-LB) in different types of lung cancer and compare the pathological results of CT-guided PNLB and surgical specimens. Methods We performed a retrospective analysis of 324 cases of lung cancer, all confirmed by CT-guided PNLB after imaging manifestation of lung-occupying lesion and treated by surgical resection.We compared the pathological results of CT-guided PNLB and surgical speci-mens. Results The total coincidence rate of the pathological result from CT-guided PNLB with that from surgical specimens was 85.8% (278/324), with even a higher coincidence rate (96.4%) in adenocarcinoma, followed by squamous cell carcinoma (86.1%), and small cell lung cancer (45.5%).Large cell lung cancer and adenosquamous carcinoma were liable to be diagnosed as adenocarcinoma by CT-guided PNLB ( 7/10 and 6/10 ) .McNemar-Bowker test revealed no significant differences in the coincidence rate in adenocarcinoma, squamous cell carcinoma, and small cell lung cancer (κ=0.837, P=0.215). Conclusion CT-guided PNLB has a high coincidence rate with surgical specimens in the pathological diagnosis of lung cancer, but the coincidence rate varies with different pathological types of the tumor.
