Comparison of Stone Metabolic Risk Factors in Recurrent Stone Formers according to Sex and Age.
- Author:
Il Oh JUN
1
;
Young Tae MOON
Author Information
1. Department of Urology, College of Medicine, Chung-Ang University, Korea. moon13579@hananet.net
- Publication Type:Original Article
- Keywords:
Stone metabolic study;
Recurrent stone former;
Sex;
Age
- MeSH:
Calcium;
Citric Acid;
Humans;
Hypercalciuria;
Incidence;
Male;
Potassium;
Risk Factors*;
Sodium;
Uric Acid;
Urolithiasis
- From:Korean Journal of Urology
2002;43(9):733-737
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: In order to compare stone metabolic risk factors in recurrent stone formers, we researched lithogenic factors according to sex and age. MATERIALS AND METHODS: We performed stone metabolic studies on recurrent stone formers (77 men, 33 women) and grouped them according to age; under 40 (n=38), from 40 to 59 (n=56) and over 60 (n=16). We evaluated excretion rate differences of lithogenic and inhibitory constituents such as volume, sodium, uric acid, calcium, oxalate, and citrate from 24-hour urine samples, and calcium, sodium, uric acid, phosphate, potassium, and chloride from serum samples. We analyzed the incidence of stone metabolic risk factors between the age groups and the sexes. RESULTS: The most common detectable risk factor in all groups of recurrent stone formers was hypocitraturia. This finding was more remarkable in males aged under 60. The incidence of hypocitraturia was higher in males and in the younger group, whereas hypercalciuria was more frequent in the elder group. CONCLUSIONS: The most important cause of urolithiasis was hypocitraturia in recurrent stone formers, and this was apparent in males aged under 60.
