Effect of traditional Chinese medicine sputum discharge liquid on preventing and treating ventilator-associated pneumonia
10.3969/j.issn.1671-9638.2016.05.007
- VernacularTitle:中药排痰液防治呼吸机相关性肺炎的临床研究
- Author:
Zhihong DING
;
Mingyan ZUO
;
Daoqin ZHUO
;
Chunlan LV
- Publication Type:Journal Article
- Keywords:
sputum discharge liquid;
ventilator-associated pneumonia;
treatment effectiveness;
traditional Chi-nese medicine
- From:
Chinese Journal of Infection Control
2016;15(5):317-320
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effect of traditional Chinese medicine sputum discharge liquid on preventing ventilator-associated pneumonia(VAP).Methods A randomized double-blind,placebo-controlled study was con-ducted,according to the inclusion and exclusion criteria,patients with respiratory failure and mechanical ventilation in the intensive care unit (ICU)of a hospital in 2011 -2014 were selected and divided into treatment group and con-trol group.Treatment group received sputum discharge liquid in addition to conventional treatment,control group adopted simulation agent based on conventional treatment.The incidence,treatment effectiveness,occurrence time, and prognosis of VAP between two groups of patients were compared.Results A total of 139 patients were monitored,70 cases in treatment group and 69 in control group.The incidence of VAP in treatment group and con-trol group were 37.14% (n =26)and 57.97%(n =40)respectively;the average onset time of VAP in treatment group and control group were (76±3.2)hours and (45±8.9)hours after admission to ICU respectively;treatment effectiveness rates in treatment and control group were 88.46% and 55.00% respectively;the incidence,occurrence time,and treatment effectiveness rates of VAP between two groups of patients were both significantly different (all P <0.05).There were no significant difference in blood routine,liver and kidney function,urine routine,stool rou-tine,and electrocardiogram results between two groups of patients (all P >0.05 ).Conclusion Intervention in patients with mechanical ventilation by sputum discharge liquid can reduce the incidence of VAP,and has a positive effect on the prognosis of disease and pulmonary infection in patients.
