Role of diffusion weighted imaging and dynamic contrast-enhanced MRI in assessing malignant and benign lesion in periamapullary regions
10.3969/j.issn.1002-1671.2016.05.019
- VernacularTitle:MR 动态增强联合扩散加权成像对壶腹区良恶性病变的鉴别
- Author:
Yan ZHOU
;
Xiangting ZENG
;
Xianheng WU
;
Shaoyan ZHENG
- Publication Type:Journal Article
- Keywords:
diffusion-weighted imaging;
dynamic contrast enhance magnetic resonance imaging;
periampullary lesions
- From:
Journal of Practical Radiology
2016;32(5):733-736
- CountryChina
- Language:Chinese
-
Abstract:
Objective To define the value of DCE and DWI in assessing malignant and benign lesion in periamapullary regions . Methods The data of dynamic contrast enhancement magnetic resonance imaging (DCE‐MRI) and diffusion‐weighted imaging(DWI) of 43 patients (32 malignant and 11 benign lesions) were analyzed retrospectively ,who have been diagnosed as biliary strictures in ampullary regions .One radiologist compared the signal intensity of DCE‐MRI and DWI of malignant and benign periamapullary le‐sions .Two other radiologists assessed data of DCE‐MRI and data of combined DCE‐MRI and DWI from those periamapullary lesions respectively .And then we compared the diagnostic sensitivity and specificity of each type of data by receiver operating characteristic (ROC) curve analysis .Results Malignant and benign periamapullary lesions showed no statistically significant difference on DCE‐MRI;Malignant periampullary lesion were more frequently appeared hyperintense than benign lesions on DWI ,and hypointense on ADC (P<0 .001) .Diagnostic accuracy improved from 84 .4% to 96 .9% and 87 .7% to 96 .6% for both reviewers after adding DWI on diagno‐sis of malignant periampuullary lesions .Conclusion The combination of DCE‐MRI and DWI can improve the diagnostic accuracy for differentiating malignant from benign strictures in the periampullary region .
