The effects of enhanced external counterpulsation on the serum level of C-reactive protein and endothe- lin-1 in patients with ischemic stroke
10.3969/j.issn.1002-0152.2016.03.001
- VernacularTitle:增强型体外反搏对缺血性脑卒中患者超敏C反应蛋白和内皮素1的影响
- Author:
Guoqiang ZHOU
;
Zongqing HUANG
;
Zhi ZHANG
;
Jianwei XIAO
;
Juan ZHANG
;
Yuguang WANG
- Publication Type:Journal Article
- Keywords:
Enhanced external counterpulsation;
Endothelin-1;
C-reactive protein;
Cerebral ischemic stroke
- From:
Chinese Journal of Nervous and Mental Diseases
2016;42(3):129-133
- CountryChina
- Language:Chinese
-
Abstract:
Objectives To explore the effects of enhanced external counterpulsation(EECP)on the serum level of C-reactive protein and endothelin-1 in patients with cerebral ischemic stroke,to provide clinical evidence for the treat?ment and secondary prevention of patients with cerebral ischemic stroke. Methods Total 187 patients with ischemic stroke were enrolled measure the serum level of C-reactive protein and endothelin-1, before EECP, after36 hours EECP, and one-month after EECP. Then contrast the difference of these indicators. Result After treatment, the serum levels of C-reactive protein and endothelin-1 in EECP group were obviously decrease and the difference was statistically signifi?cant(hs-CRP 60.1%vs. ET-1 40.9%,P<0.05). After treatment, the serum levels of C-reactive protein and endothelin-1 in EECP group were obviously decrease than that in the control group and the difference was statistically significant ( hs-CRP 41.3%vs. ET-1 24.3%,P<0.05). One-month after EECP, the serum level of endothelin-1 in EECP group was obviously decrease than that in the control group(43.8%vs. 31.8%,P<0.05). One-month after EECP, there was no signif?icant difference in the serum levels of C-reactive protein between the two groups (P>0.05). Conclusion EECP can obvi?ously reduce the serum levels of C-reactive protein and endothelin-1 in the patients with ischemic stroke, which indi?cates that EECP can slow atherosclerotic process.
