Pleiotropic protective effects of peroxisome proliferators-activated receptor γ in intracerebral hemorrhage
10.3760/cma.j.issn.1673-4165.2016.03.012
- VernacularTitle:过氧化物酶体增殖物激活受体γ在脑出血中的多效保护作用
- Author:
Li SUN
;
Shanshan CAO
;
Yanwei XU
;
Yan CHENG
- Publication Type:Journal Article
- Keywords:
Cerebral Hemorrhage;
PPARγ;
Hematoma;
Brain Edema;
Oxidative Stress;
Inflammation;
Phagocytosis;
NF-E2-Related Factor 2;
Neuroprotective Agents
- From:
International Journal of Cerebrovascular Diseases
2016;24(3):248-253
- CountryChina
- Language:Chinese
-
Abstract:
Peroxisome proliferators-activated receptor γ (PPARγ) belongs to a nuclear receptor superfamily. Many studies have shown that PPARγ can help to improve the outcome of cerebrovascular disease. PPARγ can reduce inflammatory response, oxidative stress as wel as enhance the hematoma removal abilities of microglia and macrophages, and it plays an important protective role in intracerebral hemorrhage.
