High-mobility group protein B1 and ischemic stroke
10.3760/cma.j.issn.1673-4165.2016.03.015
- VernacularTitle:高迁移率族蛋白 B1与缺血性卒中
- Author:
Xiang CAO
;
Yun XU
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemic;
HMGB1 Protein;
Inflammation
- From:
International Journal of Cerebrovascular Diseases
2016;24(3):263-267
- CountryChina
- Language:Chinese
-
Abstract:
High mobility group protein box 1 (HMGB1) is a typical nonhistone chromosomal protein. It has many celular functions in nucleus. Studies in recent years have showed that HMGB1 can be released to the outside of cels to exert a wide range of cytological effects. Ischemic stroke is one of the diseases with the highest morbidity and disability. More and more evidence has shown that HMGB1 plays a variety of important roles in the occurrence and development process of ischemic stroke. This article reviews the roles of HMGB1 in ischemic stroke.
