A preliminary study on the application of high-resolution magnetic resonance vessel wall imaging in the ;evaluation of intracranial aneurysms
10.3969/j.issn.1002-0152.2016.03.010
- VernacularTitle:高分辨磁共振血管壁成像在评估颅内动脉瘤中的初步应用
- Author:
Feng LIANG
;
Tiewei QI
;
Zhuhao LI
;
Meng WANG
;
Liqin WANG
;
Fanying LI
;
Yibin YANG
;
Siqi OU
;
Zhengsong HUANG
- Publication Type:Journal Article
- Keywords:
High-resolusion magnetic resonance;
Vessel wall imaging;
Intracranial aneurysm
- From:
Chinese Journal of Nervous and Mental Diseases
2016;42(3):175-179
- CountryChina
- Language:Chinese
-
Abstract:
Objective The present study was to investigate the feasibility of use of high resolution magnetic reso?nance vessel wall imaging(HR-VWI)in evaluation of intracranial aneurysms. Methods We prospectively collected data from patients who had intracranial aneurysms and received HR-VWI scan before surgical treatment or conservative treatment. Aneurysms were divided into ruptured group (n=12) and unruptured group (n=88). Aneurysm site, size, neck, aspect ratio(AR), daughter sac and aneurysmal wall enhancement scale were analyzed in both groups. Univariate and multivariate Logistic regression were performed to evaluate the risk factors of aneurysm rupture. Subgroup analysis was also performed to study symptomatic and asymptomatic unruptured aneurysms. Results Aneurysm size(t=2.187,P=0.031),AR(t=3.164,P=0.002),incidence of daughter sac(P=0.012) and aneurysmal wall enhancement scale(P<0.001)were higher in ruptured aneurysm group. Multivariate Logistic regression showed that aneurysmal wall enhance?ment scale was the only independent risk factor of ruptured aneurysms(P=0.002). Subgroup analysis showed aneurysm wall enhancement scale(P<0.001) and AR(t=3.939,P<0.001) were higher in symptomatic unruptured aneurysms. Conclusion Aneurysm wall enhancement on HR-VWI is more frequently seen in ruptured aneurysms and symptomatic unruptured aneurysms. Histological study is needed for better understanding of the mechanism of aneurysm wall enhance?ment.
