Risk factors for traumatic lumbar punctures in children with acute lymphoblastic leukaemia

VernacularTitle:急性淋巴细胞白血病患儿创伤性腰椎穿刺的危险因素
Author: Shan LOU ; Yu LIU ; Xuemei WANG ; Mei YAN ; Zhaoshen LI
Publication Type:Journal Article
Keywords: Acute lymphoblastic leukaemia; Traumatic lumbar punctures; Risk factors
From: The Journal of Practical Medicine 2016;32(7):1097-1100
CountryChina
Language:Chinese
Abstract: Objective To investigate the risk factors for traumatic lumbar punctures in children with acute lymphoblastic leukaemia. Methods 132 children with acute lymphoblastic leukemia totally received 2634 lumbar punctures. The basic data on age, sex, body mass index (BMI), platelet count, interval between two punctures, and presence or absence of ultrasound-guided procedure were collected and analyzed. The risk factors for traumatic lumbar puncture were identified by logistic regression. Results The risk for traumatic lumbar puncture was higher in children younger than 1 year, and it was relatively lower in those aged 1 to 10 years. The risk for traumatic lumbar puncture was slightly higher in children with a BMI index of more than 95. The longer the interval between two punctures, the lower the risk. If lumbar puncture was guided under ultrasound or radiographic images, the risk was much smaller. Conclusions Age of younger than 1 year, BMI index of more than 95, shorter interval between two punctures, and direct puncture can increase the risk for traumatic lumbar puncture.