The evaluation of the prognostic value of the18F-FDG PET/CT standard uptake value in the treatment of pancreatic cancer with tomotherapy
10.3969/J.ISSN.1672-8270.2016.04.018
- VernacularTitle:18F-FDG PET/CT标准摄取值对胰腺癌螺旋断层调强放射治疗预后的评估
- Author:
Hui ZHANG
;
Gang RENG
;
Tingyi XIA
- Publication Type:Journal Article
- Keywords:
Pancreatic carcinoma;
Tomotherapy;
Prognosis;
Prognostic value;
Fluorodeoxyglueose maximum standard uptake value;
Positron-emission tomography;
X-ray computed tomography
- From:
China Medical Equipment
2016;13(4):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the prognostic value of18F-FDG PET/CT by calculating maximal standard uptake values(SUVmax) in patients with pancreatic carcinoma of TOMO knife radiotherapy.Methods:Sixty five cases of pancreatic carcinoma who underwent18F-FDG PET/CT scan before TOMO radiotherapy were reviewed retrospectively, the18F-FDG uptake of primary tumors was measured with the SUVmax. SUVmax<3.0 was divided into group A(32 cases), SUVmax≥3.0 was divided into group B(33 cases), the relationship of SUVmax and other clinical factors with the survival of the 65 patients were analyzed.Results:By Log-rank univariate analysis showed that the differences in group A(SUVmax<3.0) and group B(SUVmax≥3.0) in patiengts with middle survival time was statistically significant(15.5:7 months)atP=0.001. TNM stages(x2=6.625,P<0.010), CA19-9(x2=10.298,P<0.001) and GTV dose(x2=8.054, P<0.005) were also statistically different at (P<0.05). Multivariate analysis showed that the SUVmax and preoperative serum CA19-9 level were independent risk factors that prevent the long-term survival of the prognosis of patients in this group.Conclusion: SUVmax has a certain clinical value in predicting the prognosis of patients with pancreatic cancer, and can guide clinical diagnosis and treatment planning, and extend the lifespan of patients with pancreatic carcinoma.
