Interaction between endometrium and embryo under the condition of in vitro co-culture during the implantation window stage
10.3969/j.issn.1006-5725.2016.07.024
- VernacularTitle:体外共培养条件下种植窗期子宫内膜与胚胎的相互作用
- Author:
Jing WANG
;
Li TAN
- Publication Type:Journal Article
- Keywords:
Co-cultured in vitro;
Endometrial cell;
Implantation window stage;
Embryo development
- From:
The Journal of Practical Medicine
2016;32(7):1115-1117
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the interaction between endometrium and embryo under the co-culture condition during the planting window stage. Methods Twenty patients who cancelled transplant for OHSS in the Reproductive Center of the second affiliated hospital of Zhengzhou university were enrolled.The discarded embryos were used to build the embryos co-culture system (Group A), with a single membrane (group B) and a single embryo(group C)as the control group. Levels of LIF and IGF expression and embryo growth were checked on 3, 4,5,6,7 day post-oocyte retrieval. Results Expressions of LIF mRNA and IGF mRNA in Group A were significantly higher than those in Group B. Embryo growth in the Group A was better than that in Group C. Conclusion Co-culture of endometrium and embryo supports the development of embryo and improves the receptivity of endometrium.
