Prognosis and its influencing factors of post-encephalitic epilepsy
- VernacularTitle:病毒性脑炎后癫痫的预后及其影响因素
- Author:
Haiyan MA
;
Yanfang ZHANG
;
Qing DI
- Publication Type:Journal Article
- Keywords:
viral encephalitis;
post-encephalitic epilepsy;
risk factors;
prognosis
- From:
Journal of Clinical Neurology
2016;29(2):120-123
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognosis and its influencing factors of post-encephalitic epilepsy ( PEE) .Methods Fifty viral encephalitis patients with PEE were followed up, which prognosis was observed by whether their no seizures for at least 1 year or not.The clinical data of patients was collected, and the relate risk factors on the poor prognosis of PEE were analyzed.Results The disturbance of consciousness and the seizure presence during acute encephalitis, more than ten seizures in poor prognosis group were much higner than the good one (all P<0.01).The age, sex, seizure type, dysphrenia and neurological defect in acute encephalitis, status epileptisus in acute encephalitis, abnormal EEG and abnormal head CT/MRI had no correlation with poor prognosis ( all P>0.05 ) .Multiple logistic regression analysis demonstrated that disturbance of consciousness during acute encephalitis、seizures presence in acute encephalitis were independent risk factors of poor outcome in PEE ( OR=7.269,95%CI:1.22 -43.35,P=0.029;OR =22.893,95%CI:4.02 -130.43,P=0.000).Conclusion Disturbance of consciousness during acute encephalitis, seizure presence in acute encephalitis both are the single risk factors of poor prognosis in PEE.
