Metoprolol administration before emergency PCI can decrease incidence rate of reperfusion arrhythmia
10.3969/j.issn.1008-0074.2016.01.22
- VernacularTitle:急诊 PCI 术前服美托洛尔降低再灌注心律失常发生率
- Author:
Zhou RONG
;
Zhou YI
- Publication Type:Journal Article
- Keywords:
Myocardial Infarction;
Angioplasty,balloon,coronary;
Reperfusion;
Arrhythmias
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2016;25(1):78-81
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore whether metoprolol administration before emergency percutaneous coronary inter‐vention (PCI) can reduce incidence rate of reperfusion arrhythmia (RA) or not .Methods :According to random number table ,a total of 80 patients with acute anterior wall myocardial infarction (age< 75 years ,baseline heart rate >70 beats/min ,no PR interval prolongation ) were randomly and equally divided into routine treatment group (didn't receive metoprolol tartrate tablet before emergency PCI ) and metoprolol group (received metoprolol tartrate tablet 25 mg before emergency PCI ) .Incidence rate of RA after PCI was compared between two groups .Results:In metoprolol group ,a total of 32 cases received PCI and eight cases received percutaneous transluminal coronary angioplasty (PTCA);in routine treatment group ,a total of 35 case received PCI and five cases received PTCA ,suc‐cess rates of both groups were 100% .In metoprolol group , RA occurred in 4 cases ,including one case with ventric‐ular fibrillation (VF);in routine treatment group , RA occurred in 15 cases ,including four cases with VF .Inci‐dence rate of RA after emergency PCI in metoprolol group was significantly lower than that of routine treatment group (10.0% vs .37.5% ,P=0.032) .Conclusion:Metoprolol administration before emergency PCI can reduce in‐cidence rate of reperfusion arrhythmia in patients with acute myocardial infarction .
